Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
- PMID: 21804868
- PMCID: PMC3135162
- DOI: 10.3762/bjoc.7.83
Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
Abstract
Continuous flow systems for hydrogenation using polysilane-supported palladium/alumina (Pd/(PSi-Al(2)O(3))) hybrid catalysts were developed. Our original Pd/(PSi-Al(2)O(3)) catalysts were used successfully in these systems and the hydrogenation of unsaturated C-C bonds and a nitro group, deprotection of a carbobenzyloxy (Cbz) group, and a dehalogenation reaction proceeded smoothly. The catalyst retained high activity for at least 8 h under neat conditions.
Keywords: flow chemistry; hydrogenation; palladium; polysilane; reduction.
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