Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011:7:886-91.
doi: 10.3762/bjoc.7.101. Epub 2011 Jun 30.

Nano copper oxide catalyzed synthesis of symmetrical diaryl sulfides under ligand free conditions

K Harsha Vardhan Reddy  1 , V Prakash Reddy, A Ashwan Kumar, G Kranthi, Yvd Nageswar
Affiliations

Nano copper oxide catalyzed synthesis of symmetrical diaryl sulfides under ligand free conditions

K Harsha Vardhan Reddy et al. Beilstein J Org Chem. 2011.

Abstract

Potassium thiocyanate acts as an efficient sulfur surrogate in C-S cross-coupling reactions mediated by recyclable copper oxide nanoparticles under ligand free conditions. This protocol avoids foul smelling thiols, for the synthesis of a variety of symmetrical diaryl sulfides, via the cross-coupling of different aryl halides with potassium thiocyanate, affording corresponding products in moderate to excellent yields.

Keywords: aryl halides; aryl sulfides; copper oxide; cross-coupling; ligand free; potassium thiocyanate; recyclable.

PubMed Disclaimer

Figures

Scheme 1
Scheme 1
Synthesis of symmetrical aryl sulfides catalyzed by copper oxide nanoparticles.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Ullmann F. Ber Dtsch Chem Ges. 1903;36:2382.
    1. Lindley J. Tetrahedron. 1984;40:1433. doi: 10.1016/S0040-4020(01)91791-0. - DOI
    1. Hassan J, Sévignon M, Gozzi C, Schulz E, Lemaire M. Chem Rev. 2002;102:1359. doi: 10.1021/cr000664r. - DOI - PubMed
    1. Johannesson P, Lindeberg G, Johansson A, Nikiforovich G V, Gogoll A, Synnergren B, Le Grèves M, Nyberg F, Karlén A, Hallberg A. J Med Chem. 2002;45:1767. doi: 10.1021/jm011063a. - DOI - PubMed
    1. Mugesh G, Du Mont W-W, Sies H. Chem Rev. 2001;101:2125. doi: 10.1021/cr000426w. - DOI - PubMed

LinkOut - more resources