Association between body mass index and risk of breast cancer in Tunisian women
- PMID: 21808117
- PMCID: PMC3156517
- DOI: 10.4103/0256-4947.83211
Association between body mass index and risk of breast cancer in Tunisian women
Erratum in
- Ann Saudi Med. 2012 Nov;32(6):665. Awatef, Msolly [corrected to Msolly, Awatef]; Olfa, Gharbi [corrected to Gharbi, Olfa]; Kacem, Mahmoudi [corrected to Mahmoudi, Kacem]; Sami, Limem [corrected to Limem, Sami]; Makram, Holchlef [corrected to Hochlef, Makram]; Slim, Ben Ahmed [corrected to B
Retraction in
-
Retraction notice.Ann Saudi Med. 2012 Nov-Dec;32(6):665. doi: 10.5144/0256-4947.2012.665. Ann Saudi Med. 2012. PMID: 23396036 Free PMC article. No abstract available.
Abstract
Background and objectives: The number of breast cancer in women has increased dramatically in Tunisia. The cause is perceived to stem from adaptation to a westernized life style which increases body mass index (BMI). This study aimed to investigate the association between BMI and breast cancer among Tunisian women.
Design and setting: Hospital-based case control study of breast cancer patients seen between November 2006 and April 2009 at the University College Hospital Farhat Hached in Sousse, Tunisia.
Patients and methods: Standardized questionnaires concerning BMI and other anthropometric data were completed on 400 breast cancer cases and 400 controls. The controls were frequency-matched to the cases by age.
Results: BMI at diagnosis was positively correlated with the risk of breast cancer among postmenopausal women (P<.001 for trend). When compared with women with a low BMI (<19), women with a BMI of 23-27 and 27-31 had a 1.7-fold (95% CI, 1.1-2.9) and 2.1-fold (95% CI, 1.1-3.9) increased risk of breast cancer, respectively, after adjustment for non-anthropometric risk factors. BMI at diagnosis was not related to the risk of breast cancer among premenopausal women. The odds ratios for premenopausal women with a BMI of 23-27 and 27-31 were 1.5 (95% CI, 0.8-2.8) and 1.3 (95% CI, 0.4-4.5), respectively. Furthermore, present BMI was not associated with breast cancer risk in either pre- and postmenopausal women.
Conclusions: Weight control in obese women may be an effective measure of breast cancer prevention in postmenopausal women.
References
-
- Ben Ahmed S, Aloulou S, Bibi M, Landolsi A, Nouira M, Ben Fatma L, et al. Breast cancer detection in Tunisian women: An analysis of a hospital trial involving 729 patients. Santé Publique. 2002;14:231–41. - PubMed
-
- Cold S, Hansen S, Overvad C, Rose C. A woman's build and risk of breast cancer. Eur J Cancer. 1998;34:1163–74. - PubMed
-
- Pathak DR, Whittemore AS. Combined effects of body size, parity, and menstrual events on breast cancer incidence in seven countries. Am J Epidemiol. 1992;135:153–67. - PubMed
-
- Trentham-Dietz A, Newcomb PA, Storer BE, Longnecker MP, Baron J, Greenberg ER, et al. Body size and risk of breast cancer. Am J Epidemiol. 1997;145:1011–9. - PubMed
-
- Peacock SL, White E, Daling JR, Voigt LF, Malone KE. Relation between obesity and breast cancer in young women. Am J Epidemiol. 1999;149:339–46. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous