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. 2011 Feb;31(1):35-8.

Prevalence of fungal infection among Iranian patients with chronic sinusitis

B Naghibzadeh  1 , E Razmpa, Sh Alavi, M Emami, M Shidfar, Gh Naghibzadeh, A Morteza
Affiliations

Prevalence of fungal infection among Iranian patients with chronic sinusitis

B Naghibzadeh et al. Acta Otorhinolaryngol Ital. 2011 Feb.

Abstract
in English, Italian

Chronic sinusitis is a major cause of morbidity today. Regional variations in the incidence of this disease have been reported. The aim of this study was to evaluate the incidence of fungal infection as the causative agent of chronic sinusitis among Iranian patients. A cross sectional hospital based study was designed; the patients underwent paranasal sinus washing and maxillary sinus biopsy. All specimens were studied by light microscopy. Fungal culturing was employed to confirm diagnosis. The patients underwent Computed Tomography for sinus evaluation. Of 162 participants, 12 samples from patients showed fungal elements, 2 of them Aspergillus fulvous (1.2%), 9 of them Alternaria species (5.56%) and 1 of them Psilomysis (0.6%). All patients presented radiologic evidence of sinusitis, ranging from mucosal thickening to total opacity. In conclusion, results obtained showed a low prevalence of fungal sinusitis among Iranian patients with chronic sinusitis. Findings also showed that Alternaria is the most causative agent.

La sinusite cronica è attualmente una patologia molto frequente, la cui incidenza è variabile da paese a paese. Lo scopo di questo studio è stato quello di valutare l'incidenza di infezione micotica come agente causale delle sinusiti croniche in Iran. A questo proposito è stato realizzato uno studio cross sectional, in cui i pazienti arruolati sono stati sottoposti a lavaggio dei seni paranasali e biopsia del seno mascellare. La coltura specifica per i miceti è stata utilizzata per la conferma diagnostica. Inoltre i pazienti sono stati sottoposti a tomografia computerizzata dei seni paranasali. Dei 162 pazienti inclusi nello studio, in 12 pazienti sono stati messi in evidenza miceti, in particolare in 2 pazienti Aspergillus fulvous (1,2%), in 9 Alternaria species (5,56%), e in un caso Psilomysis (0,6%). Tutti i pazienti presentavano segni radiologici di sinusite, variabili da un ispessimento mucoso al completo opacamento del seno mascellare. In conclusione, questo studio ha messo in evidenza globalmente una bassa incidenza di sinusiti micotiche nella popolazione iraniana; tra i miceti chiamati in causa nelle affezioni sinusali, il più frequente è rappresentato dall'Alternaria.

Keywords: Chronic sinusitis; Fungal infection; Paranasal sinuses.

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