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. 2010 Jul;2(4):233-6.
doi: 10.4103/0974-8490.69112.

Rapid preparation process of antiparkinsonian drug Mucuna pruriens silver nanoparticle by bioreduction and their characterization

Affiliations

Rapid preparation process of antiparkinsonian drug Mucuna pruriens silver nanoparticle by bioreduction and their characterization

Subramanian Arulkumar et al. Pharmacognosy Res. 2010 Jul.

Abstract

Backgorund: Development of biologically inspired experimental processes for the synthesis of nanoparticles is evolving an important branch of nanotechnology.

Methods: The bioreduction behavior of plant seed extract of Mucuna pruriens in the synthesis of silver nanoparticles was investigated employing UV/visible spectrophotometry, X-ray diffraction (XRD), and transmission electron microscopy (TEM), Fourier transform - infra red (FT- IR).

Result: M. pruriens was found to exhibit strong potential for rapid reduction of silver ions. The formation of nanoparticles by this method is extremely rapid, requires no toxic chemicals, and the nanoparticles are stable for several months.

Conclusion: The main conclusion is that the bioreduction method to produce nanoparticles is a good alternative to the electrochemical methods and it is expected to be biocompatible.

Keywords: Biosynthesis; Mucuna pruriens; nanomaterials; silver nanoparticle; transmission electron microscopy.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
UV-Vis spectrum of silver nanoparticle measured at the time of reaction of Mucuna pruriens seed extract with aqueous solution of 10-3 mol/L AgNO3.
Figure 2
Figure 2
XRD spectrum of silver nanoparticles synthesized by Mucuna pruriens seed extract.
Figure 3
Figure 3
FT-IR spectrum of silver nanoparticles synthesized by reacting AgNO3 with Mucuna pruriens seed extract.
Figure 4
Figure 4
(a) TEM images of Mucuna pruriens silver nanoparticles, (b) TEM images of particle diameter(nm) of Mucuna pruriens silver nanoparticle

References

    1. Mohanpuria P, Rana NK, Yadav SK. Biosynthesis of nanoparticles: Technological concepts and future applications. J Nanopart Res. 2008;10:507–17.
    1. Shankar SS, Rai A, Ahmad A, Sastry M. Rapid synthesis of Au, Ag, and bimetallic Au core Ag shell nanoparticles using Neem (Azadirachta indica) leaf broth. J Colloid Interface Sci. 2004;275:496–502. - PubMed
    1. Simkiss K, Wilbur KM. Biomineralization: Cell biology and mineral deposition. New York: Academic Press; 1989. p. 50.
    1. Mann S. Biomimetic Materials Chemistry. New York: VCH; 1996. p. 43.
    1. Mann S. Molecular tectonics in biomineralization and biomimetic materials chemistry. Nature. 1993;36:499.

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