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Randomized Controlled Trial
. 2011 Aug;85(2):291-4.
doi: 10.4269/ajtmh.2011.11-0056.

Adverse events after mass azithromycin treatments for trachoma in Ethiopia

Berhan Ayele  1 , Teshome Gebre, Jenafir I House, Zhaoxia Zhou, Charles E McCulloch, Travis C Porco, Bruce D Gaynor, Paul M Emerson, Thomas M Lietman, Jeremy D Keenan
Affiliations
Randomized Controlled Trial

Adverse events after mass azithromycin treatments for trachoma in Ethiopia

Berhan Ayele et al. Am J Trop Med Hyg. 2011 Aug.

Abstract

During a cluster-randomized clinical trial for trachoma in Ethiopia, two rounds of adverse event surveillance were performed in a random sample of communities after community-wide mass azithromycin treatment. The prevalence of any reported adverse event ranged from 4.9% to 7.0% in children 1-9 years of age and from 17.0% to 18.7% in persons ≥ 10 years of age. Adverse events appeared to cluster by household and perhaps by village. Mass azithromycin distributions were well tolerated in this setting.

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Conflict of interest statement

Disclosure: None of the authors has any conflicts of interest.

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