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Case Reports
. 2011 Aug;85(2):386-9.
doi: 10.4269/ajtmh.2011.10-0725.

Case reports of neuro-Chikungunya in southern Thailand

Sarunyou Chusri  1 , Pisud Siripaitoon, Siriporn Hirunpat, Khachornsakdi Silpapojakul
Affiliations
Case Reports

Case reports of neuro-Chikungunya in southern Thailand

Sarunyou Chusri et al. Am J Trop Med Hyg. 2011 Aug.

Abstract

There has been a recent increase in reports of neurologic complications as major causes of morbidity and mortality in chikungunya virus infection. As a part of 2004-2009 global outbreaks, an unprecedented large chikungunya epidemic occurred in Southern Thailand during 2008-2009 in which 49,069 cases were reported. During this period, we encountered two patients with meningoencephalitis and another patient with myeloneuropathy among 1,018 cases diagnosed as chikungunya in our hospital. The clinical pictures are presented and the key points are used to recognize and differentiate chikungunya from Japanese encephalitis virus, dengue virus, and herpesvirus infections, which are more common causes of meningoencephalitis and myelitis in this region.

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Figures

Figure 1.
Figure 1.
Axial cranial magnetic resonance imaging with fluid-attenuated inversion recovery of patient 1 showing hyper-intense signal involving both medial temporal lobes.
Figure 2.
Figure 2.
Coronal cranial magnetic resonance imaging with fluid-attenuated inversion recovery of patient 1 showing hyper-intense signal involving both insular cortices.
Figure 3.
Figure 3.
Axial cranial magnetic resonance imaging with fluid-attenuated inversion recovery of patient 2 showing confluent and large multiple hyper intense signals within both periventricular white matters.
See this image and copyright information in PMC

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