Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2011 Jul;8(7):e1001064.
doi: 10.1371/journal.pmed.1001064. Epub 2011 Jul 26.

GeneXpert--a game-changer for tuberculosis control?

Carlton A Evans  1
Affiliations
Comparative Study

GeneXpert--a game-changer for tuberculosis control?

Carlton A Evans. PLoS Med. 2011 Jul.

Abstract

Carlton Evans considers whether the new tuberculosis diagnostic test, GeneXpert, is the solution for TB control that it's said to be.

PubMed Disclaimer

Conflict of interest statement

The author declares that he has no competing interests in relation to this article. He has worked as a consultant for WHO on TB social determinants and for Médecins Sans Frontières on TB infection control and diagnostics, and has received TB-related grants from the Sir Halley Stewart Trust (TB infection control and diagnostics), Imperial Healthcare charities/IFHAD (TB control), the Wellcome Trust (TB susceptibility, infection control, and diagnostics), and FIND (partial support for developing a field TB culture test). None of these funders played any role in the preparation of this article.

References

    1. World Health Organization. Global tuberculosis control. Geneva: World Health Organization; 2010.
    1. Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, et al. Rapid molecular detection of tuberculosis and rifampin resistance. N Engl J Med. 2010;363(11):1005–1015. - PMC - PubMed
    1. Boehme CC, Nicol MP, Nabeta P, Michael JS, Gotuzzo E, et al. Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study. Lancet. 2011;377(9776):1495–1505. - PMC - PubMed
    1. Nathanson E, Nunn P, Uplekar M, Floyd K, Jaramillo E, et al. MDR tuberculosis–critical steps for prevention and control. N Engl J Med. 2010;363(11):1050–1058. - PubMed
    1. Cox H, Kebede Y, Allamuratova S, Ismailov G, Davletmuratova Z, et al. Tuberculosis recurrence and mortality after successful treatment: impact of drug resistance. PLoS Med. 2006;3(10):e384. doi: 10.1371/journal.pmed.0030384. - DOI - PMC - PubMed

MeSH terms