UneCLIPsing HuR nuclear function
- PMID: 21816340
- PMCID: PMC3156671
- DOI: 10.1016/j.molcel.2011.07.016
UneCLIPsing HuR nuclear function
Abstract
The RNA-binding protein HuR, while known to stabilize cytoplasmic mRNAs, is largely nuclear. In this issue of Molecular Cell, Mukherjee et al. (2011) and Lebedeva et al. (2011) identify transcriptome-wide HuR-RNA interactions using PAR-CLIP, unveiling HuR's nuclear role in pre-mRNA processing.
Copyright © 2011 Elsevier Inc. All rights reserved.
Figures

Comment on
-
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.Mol Cell. 2011 Aug 5;43(3):327-39. doi: 10.1016/j.molcel.2011.06.007. Epub 2011 Jun 30. Mol Cell. 2011. PMID: 21723170 Free PMC article.
-
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.Mol Cell. 2011 Aug 5;43(3):340-52. doi: 10.1016/j.molcel.2011.06.008. Epub 2011 Jun 30. Mol Cell. 2011. PMID: 21723171
References
Publication types
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous