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. 1979 Feb;6(2):625-43.
doi: 10.1093/nar/6.2.625.

Aminonucleosides and their derivatives. IV. Synthesis of the 3'-amino-3'-deoxynucleoside 5'-phosphates

A V Azhayev, A M Ozols, A S Bushnev, N B Dyatkina, S V Kochetkova, L S Victorova, M K Kukhanova, A A Krayevsky, B P Gottikh
Free PMC article

Aminonucleosides and their derivatives. IV. Synthesis of the 3'-amino-3'-deoxynucleoside 5'-phosphates

A V Azhayev et al. Nucleic Acids Res. 1979 Feb.
Free PMC article

Abstract

A new procedure has been developed for the synthesis of 3'-amino-3'-deoxyribonucleosides of adenine, cytosine and uracil by condensing the trimethylsilylated bases with peracylated 3-azido-3-deoxyribose derivative. The azido group could subsequently be reduced to amino. The 5'-phosphates of these nucleosides have been prepared and the analogues have been tested for their ability to stimulate the ribosome-catalyzed reaction of 3'(2')-O-(N-formylmethionyl) adenosine 5'-phosphate with phenylalanyl-tRNA.

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References

    1. Carbohydr Res. 1975 May;41:318-22 - PubMed
    1. Biochemistry. 1972 Dec 19;11(26):4931-7 - PubMed
    1. J Am Chem Soc. 1973 Apr 4;95(7):2333-44 - PubMed
    1. FEBS Lett. 1975 Oct 15;58(1):94-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1975 Aug;72(8):3044-8 - PubMed

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