[Research and application progress of adipose-derived stem cells]

Abstract

Objective: To review the biochemical characteristics, application progress, and prospects of the adipose-derived stem cells (ADSCs).

Methods: The recent original experimental and clinical literature about ADSCs was extensively reviewed and analyzed.

Results: ADSCs can be readily harvested in large numbers from adipose tissue with properties of stable proliferation and potential differentiation in vitro. Significant progress of ADSCs is made in the animal experiment and the clinical application. It has been widely used in the clinical treatment of cardiovascular disease, metabolic disease, encephalopathy, and tissue engineering repair.

Conclusion: ADSCs have gradually replaced bone marrow mesenchymal stem cells and become the focused hot spot of regenerative medicine and stem cells.