Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Jan;13(1):79-82.
doi: 10.1111/j.1468-1293.2011.00939.x. Epub 2011 Aug 7.

Cervical intraepithelial neoplasia and invasive cancer risks in women infected with HIV in the French West Indies

P Kadhel  1 , L Multigner, F Bardinet, Mt Goerger-Sow, E Janky
Affiliations
Free article

Cervical intraepithelial neoplasia and invasive cancer risks in women infected with HIV in the French West Indies

P Kadhel et al. HIV Med. 2012 Jan.
Free article

Abstract

Objective: The aim of the study was to assess whether HIV infection is associated with a higher risk of invasive cervical cancer (ICC).

Methods: We conducted a region-wide, population-based observational cohort study of 1232 HIV-infected women over the age of 15 years in Guadeloupe, a French Caribbean archipelago, during the period 1999-2006. The observed numbers of incident cases of cervical intraepithelial neoplasia (CIN) and ICC were compared with the expected numbers of cases based on the incidence rates for the general population, and the standardized incidence ratios (SIRs) and 95% confidence intervals (CIs) were calculated.

Results: The incidence rate of CIN was higher in the HIV-infected women than in the general population for all grades (SIR 10.1, 95% CI 6.8-14.6 for CIN grade 1; SIR 9.9, 95% CI 6.1-15.3 for CIN grade 2; and SIR 5.2, 95% CI 3.4-7.7 for CIN grade 3). However, no increase in the risk of ICC was observed (SIR 1.7, 95% CI 0.3-4.9).

Conclusions: Despite an increase in the occurrence of cervical cancer precursors, no increase in the risk of cervical cancer was found in a population of HIV-infected women who receive treatment for their infection and have access to ICC prevention services.

PubMed Disclaimer