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Review
. 2011 Sep;5(3):200-20.
doi: 10.2174/187221311797264937.

Dietary flavonoids: molecular mechanisms of action as anti- inflammatory agents

Laura Marzocchella  1 , Massimo Fantini, Monica Benvenuto, Laura Masuelli, Ilaria Tresoldi, Andrea Modesti, Roberto Bei
Affiliations
Review

Dietary flavonoids: molecular mechanisms of action as anti- inflammatory agents

Laura Marzocchella et al. Recent Pat Inflamm Allergy Drug Discov. 2011 Sep.

Abstract

Flavonoids are a large group of polyphenolic compounds, which are ubiquitously expressed in plants. They are grouped according to their chemical structure and function into flavonols, flavones, flavan-3-ols, anthocyanins, flavanones and isoflavones. Many of flavonoids are found in fruits, vegetables and beverages. Flavonoids have been demonstrated to have advantageous effects on human health because their anti-allergic, anti-inflammatory, anti-platelet aggregation, anti-tumor and anti-oxidant behavior. This report reviews the current knowledge on the molecular mechanisms of action of flavonoids as anti-inflammatory agents and also discusses the relevant patents.

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