Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Jan;1(1):21-6.
doi: 10.4103/0973-6131.36792.

Effect of yogic exercise on super oxide dismutase levels in diabetics

Affiliations

Effect of yogic exercise on super oxide dismutase levels in diabetics

Hemant H Mahapure et al. Int J Yoga. 2008 Jan.

Abstract

Context: Reactive oxygen species are known to aggravate disease progression. To counteract their harmful effects, the body produces various antioxidant enzymes, viz, superoxide dismutase, glutathione reductase etc. Literature reviews revealed that exercises help to enhance antioxidant enzyme systems; hence, yogic exercises may be useful to combat various diseases.

Aims: This study aims to record the efficacy of yoga on superoxide dismutase, glycosylated hemoglobin (Hb) and fasting blood glucose levels in diabetics.

Settings and design: Forty diabetics aged 40-55 years were assigned to experimental (30) and control (10) groups. The experimental subjects underwent a Yoga program comprising of various Asanas (isometric type exercises) and Pranayamas (breathing exercises) along with regular anti-diabetic therapy whereas the control group received anti-diabetic therapy only.

Materials and methods: Heparinized blood samples were used to determine erythrocyte superoxide dismutase (SOD) activity and glycosylated Hb levels and fasting blood specimens collected in fluoride Vacutainers were used for assessing blood glucose.

Statistical analysis used: Data were analyzed by using 2 × 2 × 3 Factorial ANOVA followed by Scheffe's posthoc test.

Results: The results revealed that Yogic exercise enhanced the levels of Superoxide dismutase and reduced glycosylated Hb and glucose levels in the experimental group as compared to the control group.

Conclusion: The findings conclude that Yogic exercises have enhanced the antioxidant defence mechanism in diabetics by reducing oxidative stress.

Keywords: Diabetes; Yogic exercises; glycosylated hemoglobin; reactive oxygen species; superoxide dismutase.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Influence of yoga training on superoxide dismutase
Figure 2
Figure 2
Reduction of glycosylated hemoglobin through yoga training

References

    1. Yu BP. Cellular defenses against damage from reactive oxygen species. Physiol Rev. 1994;74:139–62. - PubMed
    1. Halliwell B, Glutteridge JM. Free radicals in biology and medicine. 2nd ed. Oxford: Clarendon Press; 1989.
    1. Hartwig A. Role of DNA repair inhibition in lead and cadmium-induced genotoxicity: A review. Environ Health Perspect. 1994;102:45–50. - PMC - PubMed
    1. Cameron NE, Cotter MA. Potential therapeutic approaches to the treatment or prevention of diabetic neuropathy: Evidence from experimental studies. Diabet Med. 1993;10:593–605. - PubMed
    1. Lyons TJ. Glycation and oxidation: A role in pathogenesis of atherosclerosis. Am J Cardiol. 1993;71:26B–31B. - PubMed