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. 1990 Mar;221(1):44-8.
doi: 10.1007/BF00280366.

Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis

L H Johnston  1 , J H White, A L Johnson, G Lucchini, P Plevani
Affiliations

Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis

L H Johnston et al. Mol Gen Genet. 1990 Mar.

Abstract

Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis.

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