Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis
- PMID: 2183009
- DOI: 10.1007/BF00280366
Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis
Abstract
Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis.
Similar articles
-
The yeast DNA polymerase I transcript is regulated in both the mitotic cell cycle and in meiosis and is also induced after DNA damage.Nucleic Acids Res. 1987 Jul 10;15(13):5017-30. doi: 10.1093/nar/15.13.5017. Nucleic Acids Res. 1987. PMID: 3299263 Free PMC article.
-
The CDC8 transcript is cell cycle regulated in yeast and is expressed coordinately with CDC9 and CDC21 at a point preceding histone transcription.Exp Cell Res. 1987 Jul;171(1):223-31. doi: 10.1016/0014-4827(87)90265-5. Exp Cell Res. 1987. PMID: 3305044
-
Conditional mutations in the yeast DNA primase genes affect different aspects of DNA metabolism and interactions in the DNA polymerase alpha-primase complex.Genetics. 1993 Feb;133(2):183-91. doi: 10.1093/genetics/133.2.183. Genetics. 1993. PMID: 8436268 Free PMC article.
-
Transcriptional regulation of meiosis in yeast.Curr Opin Cell Biol. 2000 Jun;12(3):334-9. doi: 10.1016/s0955-0674(00)00104-6. Curr Opin Cell Biol. 2000. PMID: 10801467 Review.
-
Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe.Annu Rev Cell Biol. 1991;7:227-56. doi: 10.1146/annurev.cb.07.110191.001303. Annu Rev Cell Biol. 1991. PMID: 1809348 Review. No abstract available.
Cited by
-
Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae.Nucleic Acids Res. 1991 Sep 25;19(18):4867-72. doi: 10.1093/nar/19.18.4867. Nucleic Acids Res. 1991. PMID: 1923754 Free PMC article.
-
Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division.EMBO J. 1992 Jun;11(6):2167-76. doi: 10.1002/j.1460-2075.1992.tb05276.x. EMBO J. 1992. PMID: 1600944 Free PMC article.
-
Cell cycle-regulated transcription: effectively using a genomics toolbox.Methods Mol Biol. 2014;1170:3-27. doi: 10.1007/978-1-4939-0888-2_1. Methods Mol Biol. 2014. PMID: 24906306 Free PMC article.
-
Cell cycle expression of two replicative DNA polymerases alpha and delta from Schizosaccharomyces pombe.Mol Biol Cell. 1993 Feb;4(2):145-57. doi: 10.1091/mbc.4.2.145. Mol Biol Cell. 1993. PMID: 8443413 Free PMC article.
-
Structure and expression during development of Drosophila melanogaster gene for DNA polymerase alpha.Nucleic Acids Res. 1991 Sep 25;19(18):4991-8. doi: 10.1093/nar/19.18.4991. Nucleic Acids Res. 1991. PMID: 1923767 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases