Clinical evaluation of JCGC and TNM staging on multidetector-row computed tomography in preoperative nodal staging of gastric cancer

Abstract

Background/aims: Multidetector row computed tomography (MDCT) has emerged as a new diagnostic technology in various cancers. The aim was to evaluate its clinical compatibility with the 13th Japanese Classification of Gastric Carcinoma (JCGC), the 6th TNM and the new 14th JCGC/ 7th TNM systems in preoperative nodal staging (N-stage) of gastric cancer.

Methodology: Between January 2005 and December 2007, 92 consecutive patients with gastric cancer underwent preoperative MDCT at a slice thickness of 1.0 mm.

Results: The 13th JCGC N-stage on MDCT demonstrated the potential correlation with pathological findings (p=0.057). However, preoperative 6th TNM and the new 14th JCGC/7th TNM N-stage on MDCT from N1 to N3 did not significant correlate with pathological findings (p=0.979, 0.847) because the number of metastatic lymph nodes detected preoperatively on MDCT was significantly smaller than that detected on pathological diagnosis (p<0.0001).

Conclusions: Nodal staging in the 13th JCGC staging system correlates with histological examination better than the 6th TNM and 14th JCGC/7th TNM staging systems. The optimal preoperative nodal staging using the current 14th JCGC/7th TNM staging system on MDCT needs further investigation.