Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1990 Jan 25;18(2):305-12.
doi: 10.1093/nar/18.2.305.

Homology of lysS and lysU, the two Escherichia coli genes encoding distinct lysyl-tRNA synthetase species

F Lévêque  1 , P Plateau, P Dessen, S Blanquet
Affiliations
Free PMC article
Comparative Study

Homology of lysS and lysU, the two Escherichia coli genes encoding distinct lysyl-tRNA synthetase species

F Lévêque et al. Nucleic Acids Res. .
Free PMC article

Abstract

In Escherichia coli, two distinct lysyl-tRNA synthetase species are encoded by two genes: the constitutive lysS gene and the thermoinducible lysU gene. These two genes have been isolated and sequenced. Their nucleotide and deduced amino acid sequences show 79% and 88% identity, respectively. Codon usage analysis indicates the lysS product being more efficiently translated than the lysU one. In addition, the lysS sequence exactly coincides with the sequence of herC, a gene which is part of the prfB-herC operon. In contrast to the recent proposal of Gampel and Tzagoloff (1989, Proc. Natl. Acad. Sci. USA 86, 6023-6027), the lysU sequence is distinct from the open reading frame located adjacent to frdA, although large homologies are shared by these two genes.

PubMed Disclaimer

References

    1. Nature. 1979 Jan 25;277(5694):328 - PubMed
    1. Proc Natl Acad Sci U S A. 1989 Nov;86(21):8275-9 - PubMed
    1. Nucleic Acids Res. 1981 Jan 10;9(1):r43-74 - PubMed
    1. Gene. 1980 Dec;12(1-2):25-31 - PubMed
    1. Gene. 1980 Dec;12(1-2):33-9 - PubMed

Publication types

MeSH terms

Associated data