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Review
. 1990 Mar;6(3):92-6.
doi: 10.1016/0168-9525(90)90100-k.

Growth hormone gene regulation: a paradigm for cell-type-specific gene activation

M Karin  1 , J L Castrillo, L E Theill
Affiliations
Review

Growth hormone gene regulation: a paradigm for cell-type-specific gene activation

M Karin et al. Trends Genet. 1990 Mar.

Abstract

The growth hormone (GH) gene is specifically expressed within specialized cells of the anterior pituitary. The central role in GH gene activation is played by GHF-1, a homeodomain protein that is itself specifically expressed in the anterior pituitary.

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