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Case Reports
. 2011 Sep-Oct;59(5):379-80.
doi: 10.4103/0301-4738.83615.

Nasopalpebral lipoma coloboma syndrome

N Suresh Babu  1 , D Raviprakash, Ravi Kumar
Affiliations
Case Reports

Nasopalpebral lipoma coloboma syndrome

N Suresh Babu et al. Indian J Ophthalmol. 2011 Sep-Oct.

Abstract

Nasopalpebral lipoma-coloboma syndrome is characterized by nasopalpebral lipoma and eyelid coloboma. We report a case of a 16-year-old Indian girl who reported to us with this rare syndrome. Computed tomography scan showed a significantly hypodense lesion on the right side of nose which was confirmed to be a lipoma on histopathological examination. This condition should be included in differential diagnosis of conditions with congenital eyelid coloboma.

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Figures

Figure 1
Figure 1
Clinical photograph of the patient showing a soft lobulated mass on the right side of nose measuring 5 × 3.5 cm with normal overlying skin
Figure 2
Figure 2
Clinical photograph of the patient showing a notch on the medial end of the right lower lid measuring 7 mm at the base. The medial margin of the notch is formed by the nasal lesion. An 8 × 5 mm limbal dermoid covering nasal half of the cornea is also seen
Figure 3
Figure 3
Computed tomographic scan (axial view) of the patient showing a significantly hypodense lesion on the right side of the nose highly suggestive of lipoma
Figure 4
Figure 4
Histopathological picture of nasopalpebral lipoma showing lobules of mature adipose tissue separated by the fibrous septa H&E, ×40).
See this image and copyright information in PMC

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References

    1. Bock-Kunz AL, Lyon DB, Singhal VK, Grin TR, Park O. Nasopalpebral lipoma-coloboma syndrome. Arch Ophthalmol. 2000;118:1699–701. - PubMed
    1. Seah LL, Choo CT, Fong KS. Congenital upper lid colobomas: Management and visual outcome. Ophthal Plast Reconstr Surg. 2002;18:190–5. - PubMed

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