Alphavirus entry: NRAMP leads the way
- PMID: 21843864
- PMCID: PMC3163168
- DOI: 10.1016/j.chom.2011.07.008
Alphavirus entry: NRAMP leads the way
Abstract
The identity of the receptors that mediate alphavirus entry into host cells has been elusive. In this issue of Cell Host & Microbe, Rose et al. (2011) use a Drosophila RNAi screen to identify NRAMP, an iron transporter with 12 transmembrane domains, as a receptor for Sindbis virus in both insect and mammalian cells.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Natural resistance-associated macrophage protein is a cellular receptor for sindbis virus in both insect and mammalian hosts.Cell Host Microbe. 2011 Aug 18;10(2):97-104. doi: 10.1016/j.chom.2011.06.009. Cell Host Microbe. 2011. PMID: 21843867 Free PMC article.
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