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Comment
. 2011 Aug 18;10(2):93-4.
doi: 10.1016/j.chom.2011.08.001.

Candida albicans adds more weight to iron regulation

Jill R Blankenship  1 , Aaron P Mitchell
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Free article
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Candida albicans adds more weight to iron regulation

Jill R Blankenship et al. Cell Host Microbe. .
Free article

Abstract

The pathogen Candida albicans can occupy both the bloodstream and gastrointesintal (GI) tract, niches that differ in iron availability. Chen et al. report that a distinct transcription factor, Sef1, alters the conserved fungal iron regulatory paradigm. Sef1 is pivotal for bloodstream infection, but contributes to GI tract colonization as well.

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