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. 2011 Nov;152(5):872-6.
doi: 10.1016/j.ajo.2011.05.007. Epub 2011 Aug 16.

Improved assessment of control in intermittent exotropia using multiple measures

Sarah R Hatt  1 , Laura Liebermann, David A Leske, Brian G Mohney, Jonathan M Holmes
Affiliations

Improved assessment of control in intermittent exotropia using multiple measures

Sarah R Hatt et al. Am J Ophthalmol. 2011 Nov.

Abstract

Purpose: To develop and validate an improved measure of control in intermittent exotropia (XT).

Design: Prospective, noninterventional case series.

Methods: Twelve children with intermittent XT were evaluated during 4 sessions (2 hours apart) over a day, on 2 separate days (8 sessions per child). Control was standardized using a scoring system and quantified 3 times during each examination. Overall control for a day was calculated as the mean of all 12 measures. Single measures of control and the mean of 2 (double) and 3 (triple) measures over the examination were compared with the respective day mean, and first-day measures were compared to the second-day mean.

Results: At distance, 17% (49/287, 95% confidence interval [CI] 13% to 22%) of single measures differed from the day mean, whereas only 8% (16/191, 95 CI 5% to 13%) of double measures and 5% (5/95, 95% CI 2% to 12%) of triple measures differed. Comparing day 1 measures to overall mean for day 2, 17% (24/143, 95% CI 11% to 24%) of single measures and 17% (22/130, 95% CI 11% to 24%) of double measures differed by more than 1 level, whereas 11% (5/47, 95% CI 4% to 23%) of triple measures differed.

Conclusions: The mean of 3 assessments of control during a clinic examination better represents overall control than a single measure.

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Conflict of interest statement

Conflict of Interest: No conflicting relationship exists for any author

Figures

Figure 1
Figure 1
Correlation between Day 1 and Day 2 mean control scores in children with intermittent exotropia. For each child, the day mean was calculated as the mean of 12 measures of control across the day. Mean day scores were highly correlated at distance (Top: ICC=0.88, 95% CI 0.64 to 0.96) and moderately correlated at near (Bottom: ICC= 0.58, 95% CI 0.06 to 0.85). Dotted line represents unity line.
See this image and copyright information in PMC

References

    1. Stathacopoulos RA, Rosenbaum AL, Zanoni D, et al. Distance stereoacuity. Assessing control in intermittent exotropia. Ophthalmology. 1993;100(4):495–500. - PubMed
    1. Petrunak JL, Rao R. The evaluation of office control in intermittent exotropia: a systematic approach. Am Orthopt J. 2003;53:98–104. - PubMed
    1. Haggerty H, Richardson S, Hrisos S, Strong NP, Clarke MP. The Newcastle Control Score: a new method of grading the severity of intermittent distance exotropia. Br J Ophthalmol. 2004;88(2):233–235. - PMC - PubMed
    1. Chia A, Seenyen L, Long QB. A retrospective review of 287 consecutive children in Singapore presenting with intermittent exotropia. J AAPOS. 2005;9(3):257–263. - PubMed
    1. Mohney BG, Holmes JM. An office-based scale for assessing control in intermittent exotropia. Strabismus. 2006;14(3):147–150. - PMC - PubMed

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