DNA damage response, genetic instability and cancer: from mechanistic insights to personalized treatment
- PMID: 21843977
- PMCID: PMC5528317
- DOI: 10.1016/j.molonc.2011.07.006
DNA damage response, genetic instability and cancer: from mechanistic insights to personalized treatment
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References
-
- Ashworth, A. , Lord, C.J. , Reis-Filho, J.S. , 2011. Genetic interactions in cancer progression and treatment. Cell. 145, 30–38. - PubMed
-
- Bartek, J. , Bartkova, J. , Lukus, J. , 2007. DNA damage signalling guarda against activated oncogenes and tumour progression. Oncogene. 26, 7773–7779. - PubMed
-
- Bartkova, J. , Hamerlik, P. , Stockhausen, M.T. , Ehrmann, J. , Hlobilkova, A. , Laursen, H. , 2010. Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas. Oncogene. 29, 5095–5102. - PubMed
-
- Bartkova, J. , Horejsi, Z. , Koed, K. , Krämer, A. , Tort, F. , Zieger, K. , Guldberg, P. , Sehested, M. , Nesland, J.M. , Lukas, C. , Ørntoft, T. , Lukas, J. , Bartek, J. , 2005. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature. 434, 864–870. - PubMed
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