Comparison of three treatment regimes in schizophrenia

Abstract

90 schizophrenic patients in three regimes of thirty patients each, were treated for a period of three weeks with haloperidol alone, E.C.T. alone and E.C.T. + haloperidol in combination respectively. Rating them on R. P. scale (Rockland and Pollin, 196a) & Disability Rating Scale (Gautam, 76) showed that the E.C.T. + haloperidol receiving group was significantly better on several measures on day 8 & day 15 and also had an earlier onset of beneficial responses on "Affect & Mood" & on scores of "General appearance and behaviour". However, at the end of three weeks these differences disappeared and the three groups did not differ significantly.