Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009:2009:bcr02.2009.1579.
doi: 10.1136/bcr.02.2009.1579. Epub 2009 Aug 17.

Mirtazapine: a solution for postoperative gastroparesis?

Affiliations

Mirtazapine: a solution for postoperative gastroparesis?

Marianne Johnstone et al. BMJ Case Rep. 2009.

Abstract

This report describes the case of a 52-year-old man with an obstructed para-oesophageal hiatus hernia who required a gastropexy, who postoperatively developed gastroparesis which inadequately responded to conventional prokinetics including erythromycin, metoclopramide, ondansetron, and domperidone. The patient's symptoms were relieved rapidly with a trial of mirtazapine. A review of related literature is presented.

PubMed Disclaimer

References

    1. Parkman HP, Hasler WL, Fisher RS. American Gastroenterological Association medical position statement: diagnosis and treatment of gastroparesis. Gastroenterology 2004;127:1589–91 - PubMed
    1. Vittal H, Farrugia G, Gomez G, et al. Mechanism of the disease the pathological basis of gastroparesis – a review of experimental and clinical studies. Nat Clin Pract Gastroenterol Hepatol 2007;2:336–46 - PubMed
    1. Parishcha PJ. The riddle, mystery and enigma of gastroparesis. J Supp Oncol 2007;5:368–70 - PubMed
    1. Pae CU. Low dose mirtazapine may be successful treatment option for severe nausea and vomiting. Prog Neuro-Psychopharm Bio Psych 2006;20:1143–5 - PubMed
    1. Kim SW, Shin IS, Kim JM, et al. Mirtazapine for severe gastroparesis unresponsive to conventional prokinetic treatment. Psychosomatics 2006;47:440–2 - PubMed

LinkOut - more resources