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Review
. 2011 Sep;40(9):1137-40.
doi: 10.1007/s00256-011-1180-9. Epub 2011 Aug 17.

The osteoclast--what's new?

Nicolas A Athanasou  1
Affiliations
Review

The osteoclast--what's new?

Nicolas A Athanasou. Skeletal Radiol. 2011 Sep.

Abstract

Bone resorption is required for skeletal modelling during bone growth and for mineral homeostasis and bone remodelling throughout life. Osteoclasts are multinucleated cells that are uniquely specialised to carry out this physiological bone resorption. As osteolysis is a feature of most diseases of bone and joint, osteoclasts also play a role in pathological bone resorption, the extent of which is a function of the cellular and molecular mechanisms that govern their formation and function.

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References

    1. Histol Histopathol. 2009 Mar;24(3):337-46 - PubMed
    1. Nature. 2003 May 15;423(6937):337-42 - PubMed
    1. J Bone Joint Surg Am. 1996 Jul;78(7):1096-112 - PubMed
    1. Am J Pathol. 2007 Feb;170(2):427-35 - PubMed
    1. Rev Endocr Metab Disord. 2006 Jun;7(1-2):123-39 - PubMed

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