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. 2011 Aug 17;3(96):96cm22.
doi: 10.1126/scitranslmed.3002757.

Evaluating preclinical efficacy

Mark A Atkinson  1
Affiliations

Evaluating preclinical efficacy

Mark A Atkinson. Sci Transl Med. .

Abstract

Recent disappointing results of clinical trials seeking type 1 diabetes (T1D) reversal suggest the need for a reevaluation of our translational efforts. This Commentary explores the need for standards in evaluating therapeutic efficacy in preclinical models of T1D.

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