A new platform for death

Comment

Katharine H Wrighton. Nat Rev Mol Cell Biol. 2011.

. 2011 Aug 18;12(9):547.

doi: 10.1038/nrm3174.

No abstract available

Comment on

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs.
Tenev T, Bianchi K, Darding M, Broemer M, Langlais C, Wallberg F, Zachariou A, Lopez J, MacFarlane M, Cain K, Meier P. Tenev T, et al. Mol Cell. 2011 Aug 5;43(3):432-48. doi: 10.1016/j.molcel.2011.06.006. Epub 2011 Jul 7. Mol Cell. 2011. PMID: 21737329
cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms.
Feoktistova M, Geserick P, Kellert B, Dimitrova DP, Langlais C, Hupe M, Cain K, MacFarlane M, Häcker G, Leverkus M. Feoktistova M, et al. Mol Cell. 2011 Aug 5;43(3):449-63. doi: 10.1016/j.molcel.2011.06.011. Epub 2011 Jul 7. Mol Cell. 2011. PMID: 21737330 Free PMC article.