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. 2011:2:425-34.
doi: 10.7150/jca.2.425. Epub 2011 Aug 1.

A meta-analysis of the short- and long-term results of randomized controlled trials that compared laparoscopy-assisted and conventional open surgery for colorectal cancer

Hiroshi Ohtani  1 , Yutaka Tamamori, Yuichi Arimoto, Yukio Nishiguchi, Kiyoshi Maeda, Kosei Hirakawa
Affiliations

A meta-analysis of the short- and long-term results of randomized controlled trials that compared laparoscopy-assisted and conventional open surgery for colorectal cancer

Hiroshi Ohtani et al. J Cancer. 2011.

Abstract

Purpose: We conducted a meta-analysis to evaluate and compare the short- and long-term results of laparoscopic colorectal surgery (LCRS) and conventional open surgery (OCRS) for colorectal cancer (CRC).

Methods: We searched relevant papers published between January 1990 and May 2011. We analyzed the outcomes of each type of surgery over the short- and long-term periods.

Results: In the short-term period, we found no significant differences in overall perioperative complications and anastomotic leakage between LCRS and OCRS groups. We found no significant differences in overall, distant, local and wound-site recurrence, overall mortality, 3 and 5 year disease-free survival rate, and cancer-related mortality between the 2 groups.

Conclusions: LCRS has the benefits of reducing intraoperative blood loss, earlier resumption of oral intake, and shorter duration of hospital stay in the short-term. The long-term outcomes of LCRS seem to be similar to those of OCRS.

Keywords: colorectal cancer; laparoscopy-assisted colorectal surgery; meta-analysis.

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Conflict of interest statement

Conflict of Interest: The authors have declared that no conflict of interest exists.

Figures

Fig 1
Fig 1
Meta-analysis of the short-term period for colorectal cancer
Fig 1
Fig 1
Meta-analysis of the short-term period for colorectal cancer
Fig 1
Fig 1
Meta-analysis of the short-term period for colorectal cancer
Fig 2
Fig 2
Meta-analysis of the long- term period for colorectal cancer
Fig 2
Fig 2
Meta-analysis of the long- term period for colorectal cancer
Fig 2
Fig 2
Meta-analysis of the long- term period for colorectal cancer
See this image and copyright information in PMC

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