doi: 10.1042/bj1761007.
Thyroid-hormone modulation of the number of beta-adrenergic receptors in rat fat-cell membranes
- PMID: 218550
- PMCID: PMC1186327
- DOI: 10.1042/bj1761007
Item in Clipboard
Thyroid-hormone modulation of the number of beta-adrenergic receptors in rat fat-cell membranes
Biochem J.
.
Abstract
Adipocytes from thyroidectomized rats contain 3 times less [3H]dihydroalprenolol-binding sites (beta-adrenergic receptors) than adipocytes from euthyroid animals. This alteration is not solely due to cell-size differences, but also to a thyroidectomy-induced defect in beta-adrenergic receptor density per adipocyte surface area, a defect that is furthermore corrected by tri-iodothyronine treatment.
Similar articles
-
Thyroid hormone regulation of beta-adrenergic receptor number in aging rats.Endocrinology. 1981 Apr;108(4):1276-8. doi: 10.1210/endo-108-4-1276. Endocrinology. 1981. PMID: 6258903
-
Thyroid hormone regulation of beta-adrenergic receptor number.J Biol Chem. 1977 Apr 25;252(8):2787-9. J Biol Chem. 1977. PMID: 15999
-
beta-Adrenergic and muscarinic cholinergic receptors in rat submaxillary glands. Effects of thyroidectomy.Biochim Biophys Acta. 1979 Feb 19;583(1):129-32. doi: 10.1016/0304-4165(79)90317-9. Biochim Biophys Acta. 1979. PMID: 217446
-
Is the adipocyte beta-adrenoceptor a prototype for the recently cloned atypical 'beta 3-adrenoceptor'?Trends Pharmacol Sci. 1990 Jan;11(1):3-7. doi: 10.1016/0165-6147(90)90032-4. Trends Pharmacol Sci. 1990. PMID: 2155496 Review. No abstract available.
-
Differential recruitment and differential regulation by physiological amines of fat cell beta-1, beta-2 and beta-3 adrenergic receptors expressed in native fat cells and in transfected cell lines.Cell Signal. 1994 May;6(4):363-92. doi: 10.1016/0898-6568(94)90085-x. Cell Signal. 1994. PMID: 7946963 Review. No abstract available.
Cited by
-
Thyroid hormone action on intermediary metabolism. Part II: Lipid metabolism in hypo- and hyperthyroidism.Klin Wochenschr. 1984 Jan 16;62(2):49-55. doi: 10.1007/BF01769663. Klin Wochenschr. 1984. PMID: 6708390
-
Leptin, thyrotropin, and thyroid hormones in obese/overweight women before and after two levels of energy deficit.Endocrine. 2004 Jul;24(2):147-53. doi: 10.1385/ENDO:24:2:147. Endocrine. 2004. PMID: 15347841
-
Beta-adrenergic receptors and isoproterenol-stimulated potassium transport in erythrocytes from normal and hypothyroid turkeys. Quantitative relation between receptor occupancy and physiologic responsiveness.J Clin Invest. 1980 Nov;66(5):1057-64. doi: 10.1172/JCI109934. J Clin Invest. 1980. PMID: 6253521 Free PMC article.
-
Changes in the anti-lipolytic action and binding to plasma membranes of N6-L-phenylisopropyladenosine in adipocytes from starved and hypothyroid rats.Biochem J. 1984 Oct 1;223(1):53-9. doi: 10.1042/bj2230053. Biochem J. 1984. PMID: 6497845 Free PMC article.
-
Effects of thyroid function on submaxillary gland sensitivity to autonomic nervous drugs.J Endocrinol Invest. 1982 Jan-Feb;5(1):5-11. doi: 10.1007/BF03350475. J Endocrinol Invest. 1982. PMID: 7047632
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
