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Review
. 2011 Sep;36(4):731-7.
doi: 10.1007/s12038-011-9097-y.

Animal models for the study of arterial hypertension

Waleska C Dornas  1 , Marcelo E Silva
Affiliations
Review

Animal models for the study of arterial hypertension

Waleska C Dornas et al. J Biosci. 2011 Sep.

Abstract

Hypertension is one of the leading causes of disability or death due to stroke, heart attack and kidney failure. Because the etiology of essential hypertension is not known and may be multifactorial, the use of experimental animal models has provided valuable information regarding many aspects of the disease, which include etiology, pathophysiology, complications and treatment. The models of hypertension are various, and in this review, we provide a brief overview of the most widely used animal models, their features and their importance.

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