Eccrine porocarcinoma of the lower extremity: a case report and review of literature

Abstract

Eccrine porocarcinoma is a rare malignancy of the eccrine sweat gland. It is usually found frequently on the lower extremities, and it affects both sexes equally usually in the sixth to seventh decade. In our case, we present a 42-year-old male patient with a recurring exophytic tumor on the right lower extremity without local extension. The initial tumor was biopsied, excised and diagnosed as an eccrine poroma. The tumor then recurred 6 years later, was re-excised, reconstructed with a soleus muscle flap and diagnosed as an eccrine porocarcinoma.

Figure 1

Preoperative image of the pink exophytic outgrowth - 2.0 × 3.0 cm.

Figure 2

The tumor cells are in-situ and invasive. Malignant eosinophilic lobular masses or islands are seen with eosinophilic cells that are polyhedral and fusiform that have variable cytoplasm, hyperchromatic nuclei and indistinct cell boundaries.

Figure 3

High power view show invasive carcinoma cells. There is obvious cell atypia with many mitotic figures seen. The squamous cells have variable differentiation accompanied with changes in pigmentation that are aligned in a horizontal nodular pattern. Both carcinoma in situ and invasive component noted.

Figure 4

Postoperative image of the excised area with a soleus muscle flap reconstruction.