Mechanism of antibody-mediated viral clearance in immunotherapy of respiratory syncytial virus infection of cotton rats
- PMID: 2186179
- PMCID: PMC249499
- DOI: 10.1128/JVI.64.6.3091-3092.1990
Mechanism of antibody-mediated viral clearance in immunotherapy of respiratory syncytial virus infection of cotton rats
Abstract
Antibody-mediated clearance of respiratory syncytial virus from cotton rat pulmonary tissues occurs in the absence of complement and in the absence of the Fc portion of the immunoglobulin G molecule, suggesting that complement-independent, cell-independent neutralization is the major mechanism of clearance.
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