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. 2011 Sep;197(3):W482-8.
doi: 10.2214/AJR.10.5428.

Small serotonin-producing neuroendocrine tumor of the pancreas associated with pancreatic duct obstruction

Satomi Kawamoto  1 , Chanjuan Shi, Ralph H Hruban, Michael A Choti, Richard D Schulick, Elliot K Fishman, Stanley S Siegelman
Affiliations

Small serotonin-producing neuroendocrine tumor of the pancreas associated with pancreatic duct obstruction

Satomi Kawamoto et al. AJR Am J Roentgenol. 2011 Sep.

Abstract

Objective: Pancreatic neuroendocrine tumors expressing serotonin (carcinoid tumors) account for a small portion of pancreatic neuroendocrine tumors. The purpose of this study was to describe cases of small serotonin-producing pancreatic neuroendocrine tumors associated with pancreatic duct obstruction.

Conclusion: Serotonin produced by pancreatic neuroendocrine tumors can induce fibrosis and pancreatic duct obstruction. Pancreatic neuroendocrine tumors should be considered when CT shows a small hypervascular mass associated with upstream pancreatic duct dilatation or atrophy. Evidence of small pancreatic neuroendocrine tumors should be sought in cases of idiopathic pancreatic duct stenosis.

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