This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Comment

. 2011 Aug 24;11(9):621.

doi: 10.1038/nrc3128.

Metabolism: flexible flux

Sarah Seton-Rogers

PMID: 21863045
DOI: 10.1038/nrc3128

Comment

Metabolism: flexible flux

Sarah Seton-Rogers. Nat Rev Cancer. 2011.

. 2011 Aug 24;11(9):621.

doi: 10.1038/nrc3128.

Author

Sarah Seton-Rogers

PMID: 21863045
DOI: 10.1038/nrc3128

No abstract available

PubMed Disclaimer

Comment on

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. Possemato R, et al. Nature. 2011 Aug 18;476(7360):346-50. doi: 10.1038/nature10350. Nature. 2011. PMID: 21760589 Free PMC article.
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Locasale JW, et al. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. Nat Genet. 2011. PMID: 21804546 Free PMC article.

Similar articles

Response of the central metabolism of Corynebacterium glutamicum to different flux burdens.
Marx A, Striegel K, de Graaf AA, Sahm H, Eggeling L. Marx A, et al. Biotechnol Bioeng. 1997 Oct 20;56(2):168-80. doi: 10.1002/(SICI)1097-0290(19971020)56:2<168::AID-BIT6>3.0.CO;2-N. Biotechnol Bioeng. 1997. PMID: 18636622
Metabolic flux responses to deletion of 20 core enzymes reveal flexibility and limits of E. coli metabolism.
Long CP, Antoniewicz MR. Long CP, et al. Metab Eng. 2019 Sep;55:249-257. doi: 10.1016/j.ymben.2019.08.003. Epub 2019 Aug 4. Metab Eng. 2019. PMID: 31390539
The metabolic flux phenotype of heterotrophic Arabidopsis cells reveals a flexible balance between the cytosolic and plastidic contributions to carbohydrate oxidation in response to phosphate limitation.
Masakapalli SK, Bryant FM, Kruger NJ, Ratcliffe RG. Masakapalli SK, et al. Plant J. 2014 Jun;78(6):964-77. doi: 10.1111/tpj.12522. Epub 2014 May 21. Plant J. 2014. PMID: 24674596
Metabolic flux analysis using mass spectrometry.
Wittmann C. Wittmann C. Adv Biochem Eng Biotechnol. 2002;74:39-64. doi: 10.1007/3-540-45736-4_3. Adv Biochem Eng Biotechnol. 2002. PMID: 11991183 Review.
Regulation of glycolytic flux and overflow metabolism depending on the source of energy generation for energy demand.
Shimizu K, Matsuoka Y. Shimizu K, et al. Biotechnol Adv. 2019 Mar-Apr;37(2):284-305. doi: 10.1016/j.biotechadv.2018.12.007. Epub 2018 Dec 18. Biotechnol Adv. 2019. PMID: 30576718 Review.

See all similar articles

Cited by

Phosphoglycerate dehydrogenase: potential therapeutic target and putative metabolic oncogene.
Zogg CK. Zogg CK. J Oncol. 2014;2014:524101. doi: 10.1155/2014/524101. Epub 2014 Dec 9. J Oncol. 2014. PMID: 25574168 Free PMC article. Review.

References

1. Nature. 2011 Aug 18;476(7360):346-50 - PubMed
1. Nat Genet. 2011 Jul 31;43(9):869-74 - PubMed

Publication types

Actions

LinkOut - more resources

Full Text Sources
- Nature Publishing Group