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Randomized Controlled Trial
. 2011 Oct;26(5):923-36.
doi: 10.1093/her/cyr061. Epub 2011 Aug 23.

Challenges to recruitment and retention of African Americans in the gene-environment trial of response to dietary interventions (GET READI) for heart health

Betty M Kennedy  1 , David W Harsha, Ebony B Bookman, Yolanda R Hill, Tuomo Rankinen, Ruben Q Rodarte, Connie D Murla
Affiliations
Randomized Controlled Trial

Challenges to recruitment and retention of African Americans in the gene-environment trial of response to dietary interventions (GET READI) for heart health

Betty M Kennedy et al. Health Educ Res. 2011 Oct.

Abstract

In this paper, challenges to recruiting African Americans specifically for a dietary feeding trial are examined, learning experiences gained and suggestions to overcome these challenges in future trials are discussed. A total of 333 individuals were randomized in the trial and 234 (167 sibling pairs and 67 parents/siblings) completed the dietary intervention and required DNA blood sampling for genetic analysis. The trial used multiple strategies for recruitment. Hand distributed letters and flyers through mass distribution at various churches resulted in the largest number (n = 153, 46%) of African Americans in the trial. Word of mouth accounted for the second largest number (n = 120, 36%) and included prior study participants. These two recruitment sources represented 82% (n = 273) of the total number of individuals randomized in GET READI. The remaining 18% (n = 60) consisted of a combination of sources including printed message on check stubs, newspaper articles, radio and TV appearances, screening events and presentations. Though challenging, the recruitment efforts for GET READI produced a significant number of African American participants despite the inability to complete the trial as planned because of low recruitment yields. Nevertheless, the recruitment process produced substantial numbers that successfully completed all study requirements.

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References

    1. Kennedy BM, Conlin PR, Ernst D, et al. Successfully recruiting a multicultural population: the DASH-sodium experience. Ethn Dis. 2004;15:123–9. - PubMed
    1. Cosgrove N, Borhani NO, Bailey G, et al. Mass mailing and staff experience in a total recruitment program for a clinical trial: the SHEP experience. Control Clin Trials. 1999;20:133–48. - PubMed
    1. Valanis B, Blank J, Glass A. Mailing strategies and costs of recruiting heavy smokers in CARET, a large chemoprevention trial. Control Clin Trials. 1998;19:25–38. - PubMed
    1. Ramasubbu K, Gurn H, Litaker D. Gender bias in clinical trials: do double standards still apply? J Womens Health Gender Based Med. 2001;10:757–64. - PubMed
    1. Lovato LC, Hill K, Hertert S, et al. Recruitment for controlled clinical trials: literature summary and annotated bibliography. Control Clin Trials. 1997;18:328–52. - PubMed

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