Comment
doi: 10.1016/j.immuni.2011.08.006.
When the going gets tough, memory T cells check out
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- PMID: 21867925
- DOI: 10.1016/j.immuni.2011.08.006
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Comment
When the going gets tough, memory T cells check out
Immunity.
.
Free article
Abstract
Memory CD8(+) T cells proliferate faster than naive cells to rapidly control an infectious challenge, but West et al. (2011) in this issue of Immunity report that this superiority is lost in the face of a high dose or chronic viral challenge.
Copyright © 2011 Elsevier Inc. All rights reserved.
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Memory T cells: new insights into the molecular basis of sensitivity and heterogeneity.Am J Transplant. 2012 Jun;12(6):1361. doi: 10.1111/j.1600-6143.2012.04151.x. Am J Transplant. 2012. PMID: 22642469 No abstract available.
Comment on
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Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load.Immunity. 2011 Aug 26;35(2):285-98. doi: 10.1016/j.immuni.2011.05.017. Immunity. 2011. PMID: 21856186 Free PMC article.
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