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. 2012 Feb;51(2):160-4.
doi: 10.1177/0009922811418823. Epub 2011 Aug 25.

Detours on the road to diagnosis of Graves disease

Emily K Sims  1 , Erica A Eugster, Todd D Nebesio
Affiliations

Detours on the road to diagnosis of Graves disease

Emily K Sims et al. Clin Pediatr (Phila). 2012 Feb.

Abstract

Objectives: The aims of this study were to determine the frequency at which spurious diagnoses and unnecessary treatment occurs prior to the diagnosis of Graves disease (GD) and to evaluate the economic consequences of these events.

Methods: Retrospective chart review of children diagnosed with GD.

Results: A total of 76 children (61 girls) aged 11.9 ± 3.8 years were identified. In all, 17 (22.4%) were referred to other subspecialists prior to diagnosis of GD. Six were hospitalized, and 2 visited emergency rooms. A total of 15 (19.7%) underwent nonthyroid-related studies. Estimated cost of testing and procedures ranged from $49 to $14,000. Twelve (15.8%) were diagnosed with attention deficit/hyperactivity disorder, and 16 (21.1%) were started on medications for other conditions prior to diagnosis of GD.

Conclusions: Evaluation and treatment for presumed other disorders are common in children with GD. A high index of suspicion for hyperthyroidism by primary care providers may help to avoid clinical detours that may be costly and delay diagnosis.

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Conflict of interest statement

Declaration of Conflicting Interests

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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