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Review
. 2011 Sep;38(3):383-94, vii.
doi: 10.1016/j.pop.2011.05.001.

Peptic ulcer disease

Wadie I Najm  1
Affiliations
Review

Peptic ulcer disease

Wadie I Najm. Prim Care. 2011 Sep.

Abstract

Peptic ulcer disease (PUD) is due mostly to the widespread use of low-dose aspirin and nonsteroidal anti-inflammator drugs. It occurs mostly in older patients and those with comorbidities. Pain awakening the patient from sleep between 12 and 3 a.m. affects two-thirds of duodenal ulcer patients and one-third of gastric ulcer patients. Older adults (>80 years old) with PUD often do not present with abdominal pain; instead, epigastric pain, nausea and vomiting are among their most common presenting symptoms.

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