Acquired hemophilia A
- PMID: 21874757
- DOI: 10.1016/b978-0-12-387025-4.00003-0
Acquired hemophilia A
Abstract
Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs. In this review the actual knowledge on diagnostic and therapeutic aspects of this disease will be summarized.
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