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Review
. 2011:54:71-80.
doi: 10.1016/b978-0-12-387025-4.00003-0.

Acquired hemophilia A

Affiliations
Review

Acquired hemophilia A

Massimo Franchini et al. Adv Clin Chem. 2011.

Abstract

Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs. In this review the actual knowledge on diagnostic and therapeutic aspects of this disease will be summarized.

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