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. 2011 Nov;55(11):5388-91.
doi: 10.1128/AAC.05517-11. Epub 2011 Aug 29.

Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand

Vanaporn Wuthiekanun  1 , Premjit Amornchai, Natnaree Saiprom, Narisara Chantratita, Wirongrong Chierakul, Gavin C K W Koh, Wipada Chaowagul, Nicholas P J Day, Direk Limmathurotsakul, Sharon J Peacock
Affiliations

Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand

Vanaporn Wuthiekanun et al. Antimicrob Agents Chemother. 2011 Nov.

Abstract

A 21-year survey conducted in northeast Thailand of antimicrobial resistance to parenteral antimicrobial drugs used to treat melioidosis identified 24/4,021 (0.6%) patients with one or more isolates resistant to ceftazidime (n = 8), amoxicillin-clavulanic acid (n = 4), or both drugs (n = 12). Two cases were identified at admission, and the remainder were detected a median of 15 days after starting antimicrobial therapy. Resistance to carbapenem drugs was not detected. These findings support the current prescribing recommendations for melioidosis.

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References

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