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Meta-Analysis
. 2011 Jul 28;17(28):3359-65.
doi: 10.3748/wjg.v17.i28.3359.

Laparoscopic fenestration vs open fenestration in patients with congenital hepatic cysts: a meta-analysis

Jian-Guo Qiu  1 , Hong Wu, Hui Jiang, Ji-Wei Huang, Prasoon Pankaj, Ying-Long Xu, Jing-Zhou Wang, Yong Zeng
Affiliations
Meta-Analysis

Laparoscopic fenestration vs open fenestration in patients with congenital hepatic cysts: a meta-analysis

Jian-Guo Qiu et al. World J Gastroenterol. .

Abstract

Aim: To determine whether the outcomes of laparoscopic fenestration (LF) were superior to open fenestration (OF) for congenital liver cysts.

Methods: Comparative studies published between January 1991 and May 2010 on Medline (Ovid), Emsco, PubMed, Science Direct; Cochrane Reviews; CNKI; Chinese Biomedical Database, VIP and other electronic databases were searched. Randomized controlled trials (RCTs) and retrospective case-control studies on the management of congenital hepatic cysts were collected according to the pre-determined eligibility criteria to establish a literature database. Retrieval was ended in May 2010. Meta-analysis was performed using RevMan 5.0 software (Cochrane library).

Results: Nine retrospective case-control studies involving 657 patients, comparing LF with OF were included for the final pooled analysis. The meta-analysis results showed less operative time [mean difference (MD): -28.76, 95% CI: -31.03 to 26.49, P < 0.00001]; shorter hospital stay (MD: -3.35, 95% CI: -4.46 to -2.24, P < 0.00001); less intraoperative blood loss (MD: -40.18, 95% CI: -52.54 to -27.82, P < 0.00001); earlier return to regular diet (MD: -29.19, 95% CI: -30.65 to -27.72, P < 0.00001) and activities after operation (MD: -21.85, 95% CI: -31.18 to -12.51, P < 0.0001) in LF group; there was no significant difference between the two groups in postoperative complications (odds ratio: 0.99, 95% CI: 0.41 to 2.38, P = 0.98) and cysts recurrence rates.

Conclusion: The short-term outcomes of LF for patients with congenital hepatic cysts were superior to open approach, but its long-term outcomes should be verified by further RCTs and extended follow-up.

Keywords: Congenital hepatic cysts; Laparoscopic fenestration; Meta-analysis; Open fenestration; Systematic review.

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Figures

Figure 1
Figure 1
Flow chart for literature screening.
Figure 2
Figure 2
Meta-analysis of all available data in operative time.
Figure 3
Figure 3
Meta-analysis of all available data in hospital stay.
Figure 4
Figure 4
Meta-analysis of all available data in intraoperative blood loss.
Figure 5
Figure 5
Meta-analysis of all available data in the time to return to normal diet.
Figure 6
Figure 6
Meta-analysis of all available data in the time to return to normal activities.
Figure 7
Figure 7
Meta-analysis of all available data in the incidence of complications.
See this image and copyright information in PMC

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