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. 2011:2011:891342.
doi: 10.1155/2011/891342. Epub 2011 Aug 17.

Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes

Chris M Cirimotich  1 , April M Clayton, George Dimopoulos
Affiliations

Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes

Chris M Cirimotich et al. J Trop Med. 2011.

Abstract

Current efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on two approaches to malaria control, a low-tech strategy based on parasite inhibition by the mosquito's natural microflora, and a high-tech strategy using genetic modification of mosquitoes that renders them resistant to infection and discuss advantages and disadvantages for both approaches.

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