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Editorial
. 2011 Sep;96(9):1241-3.
doi: 10.3324/haematol.2011.050526.

Acute myeloid leukemia with expanded erythropoiesis

Anna Porwit, James W Vardiman
Editorial

Acute myeloid leukemia with expanded erythropoiesis

Anna Porwit et al. Haematologica. 2011 Sep.
No abstract available

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Figures

Figure 1.
Figure 1.
A 63-year-old woman presented with pancytopenia, including severe anemia (Hb=5g/dL). A bone marrow aspirate (A) and biopsy (B) were obtained. There were 82% erythroid precursors and 8% blasts (57% of the non-erythroid cells). A diagnosis of AEL was made. The patient received multiple units of packed red cells but no definitive therapy, and 6 days later was transferred to a tertiary care center for further treatment. At that time, Hb=9.8g/dL. A repeat aspirate (C) and biopsy (D) were performed and showed that erythroid precursors accounted for 42% of the marrow cells and blasts for 16%. The patient had a complex karyotype (56, XY) with gains of numerous chromosomes, including +8 and +9, loss of chromosome 22, and structural abnormalities of chromosomes 3 and 7. A diagnosis of refractory anemia with excess of blasts-2 was made.
See this image and copyright information in PMC

Comment on

References

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