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. 2011 Nov;49(11):3967-70.
doi: 10.1128/JCM.01310-11. Epub 2011 Aug 31.

Xpert MTB/RIF for rapid diagnosis of tuberculous lymphadenitis from fine-needle-aspiration biopsy specimens

Louis J Ligthelm  1 , Mark P Nicol, Kim G P Hoek, Rachael Jacobson, Paul D van Helden, Ben J Marais, Robin M Warren, Colleen A Wright
Affiliations

Xpert MTB/RIF for rapid diagnosis of tuberculous lymphadenitis from fine-needle-aspiration biopsy specimens

Louis J Ligthelm et al. J Clin Microbiol. 2011 Nov.

Abstract

This study demonstrates the excellent diagnostic accuracy of the Xpert MTB/RIF test in patients with tuberculous lymphadenitis. The test sensitivity and specificity were 96.7% (95% confidence interval [CI], 86.6 to 100%) and 88.9% (95% CI, 69.6 to 100%), respectively, and it correctly identified 6/6 (100%) of the cytology smear-negative/culture-positive cases and 1 of 2 (50%) rifampin-resistant cases.

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Figures

Fig. 1.
Fig. 1.
Flow diagram of all patients referred for fine-needle aspiration biopsy with possible mycobacterial lymphadenitis.
See this image and copyright information in PMC

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