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. 2011 Nov;49(11):3983-5.
doi: 10.1128/JCM.05552-11. Epub 2011 Aug 31.

Clinical validation of the cobas 4800 HPV test for cervical screening purposes

D A M Heideman  1 , A T Hesselink, J Berkhof, F van Kemenade, W J G Melchers, N Fransen Daalmeijer, M Verkuijten, C J L M Meijer, P J F Snijders
Affiliations

Clinical validation of the cobas 4800 HPV test for cervical screening purposes

D A M Heideman et al. J Clin Microbiol. 2011 Nov.

Abstract

This study shows that the clinical performance and reproducibility of the cobas 4800 HPV test for high-risk human papillomavirus (HPV) detection fulfill the criteria as formulated in international guidelines of HPV test requirements for cervical screening purposes. Accordingly, the cobas 4800 HPV test can be considered clinically validated for cervical screening.

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References

    1. Castle P. E., et al. 2009. Evaluation of a prototype real-time PCR assay for carcinogenic human papillomavirus (HPV) detection and simultaneous HPV genotype 16 (HPV16) and HPV18 genotyping. J. Clin. Microbiol. 47:3344–3347 - PMC - PubMed
    1. Mateos M. L., de Chacon A. J., Rodriguez-Dominguez M., Sanz I., Rubio M. D. 2011. Evaluation of a prototype real-time PCR assay for the separate detection of human papilloma virus genotypes 16 and 18 and other high risk human papillomavirus in cervical cancer screening. Enferm. Infecc. Microbiol. Clin. 29:411–414 - PubMed
    1. Meijer C. J., Berkhof H., Heideman D. A., Hesselink A. T., Snijders P. J. 2009. Validation of high-risk HPV tests for primary cervical screening. J. Clin. Virol. 46(Suppl. 3):S1–S4 - PubMed
    1. Meijer C. J., et al. 2009. Guidelines for human papillomavirus DNA test requirements for primary cervical cancer screening in women 30 years and older. Int. J. Cancer 124:516–520 - PMC - PubMed
    1. Rijkaart D. C., et al. 2011. Evaluation of 14 triage strategies for HPV DNA-positive women in population-based cervical screening. Int. J. Cancer [Epub ahead of print.] doi: - DOI - PubMed

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