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Review
. 1990 Apr;77(4):170-5.
doi: 10.1007/BF01131159.

Evolving trends in steroid hormone receptor research

M K Agarwal  1
Affiliations
Review

Evolving trends in steroid hormone receptor research

M K Agarwal. Naturwissenschaften. 1990 Apr.

Abstract

Recent advances have challenged classical notions regarding the nature of steroid hormone receptors in the cell including localization, activation, configuration, and stability. Molecular biology has revealed a remarkable similarity in the primary structure of a wide variety of receptor classes that goes beyond steroid action. Post-translational modification of a primary unit, expressed in response to genetic conservatism, would appear to assure receptor dynamics specific to hormone-, organ-, and tissue-dependent processes, and may even lead to toxicity and oncogenicity.

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