doi: 10.1111/j.1747-0285.2011.01231.x.
Epub 2011 Sep 21.
Synthesis and antibacterial activity of aromatic and heteroaromatic amino alcohols
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- PMID: 21883957
- DOI: 10.1111/j.1747-0285.2011.01231.x
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Synthesis and antibacterial activity of aromatic and heteroaromatic amino alcohols
Chem Biol Drug Des.
2011 Nov.
Abstract
Two series of aromatic and heteroaromatic amino alcohols were synthesized from alcohols and aldehydes and evaluated for their antibacterial activities. All the octylated compounds displayed a better activity against the four bacteria tested when evaluated by the agar diffusion method and were selected for the evaluation of minimal inhibitory concentration. The best results were obtained for p-octyloxybenzyl derivatives against Staphylococcus epidermidis (minimal inhibitory concentrations = 32 μm).
© 2011 John Wiley & Sons A/S.
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