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. 2011 Nov;78(5):876-80.
doi: 10.1111/j.1747-0285.2011.01231.x. Epub 2011 Sep 21.

Synthesis and antibacterial activity of aromatic and heteroaromatic amino alcohols

Camila G de Almeida  1 , Samira G Reis, Angelina M de Almeida, Claudio G Diniz, Vânia L da Silva, Mireille Le Hyaric
Affiliations

Synthesis and antibacterial activity of aromatic and heteroaromatic amino alcohols

Camila G de Almeida et al. Chem Biol Drug Des. 2011 Nov.

Abstract

Two series of aromatic and heteroaromatic amino alcohols were synthesized from alcohols and aldehydes and evaluated for their antibacterial activities. All the octylated compounds displayed a better activity against the four bacteria tested when evaluated by the agar diffusion method and were selected for the evaluation of minimal inhibitory concentration. The best results were obtained for p-octyloxybenzyl derivatives against Staphylococcus epidermidis (minimal inhibitory concentrations = 32 μm).

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