Basal synaptic transmission: astrocytes rule!
- PMID: 21884929
- DOI: 10.1016/j.cell.2011.08.006
Basal synaptic transmission: astrocytes rule!
Abstract
In this issue, Panatier et al. (2011) show that astrocytes detect synaptic activity induced by single action potentials and upregulate basal synaptic transmission through calcium-dependent mechanisms and purinergic signaling. These results demonstrate the relevance of astrocyte calcium in neurophysiology and confirm that astrocytes are actively involved in synaptic function.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Astrocytes are endogenous regulators of basal transmission at central synapses.Cell. 2011 Sep 2;146(5):785-98. doi: 10.1016/j.cell.2011.07.022. Cell. 2011. PMID: 21855979
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